Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or, when the plant is under attack by pathogens such as bacteria or fungi. Sources of resveratrol in food include the skin of grapes, blueberries, raspberries, mulberries.
Studies in resveratrol have shown evidence of potential efficacy against cancer cells growth in human body. Other studies have shown positive effects of the substance in diseases such as atherosclerosis, heart disease, arthritis and some autoimmune diseases.
In an animal study, mice were given a high-fat diet. Co-administration of resveratrol significantly reduced weight gain. At particularly high resveratrol doses, a doubling of endurance performance was observed.
Resveratrol acts on NF-kB so that they can no longer develop their survival effect. This in turn leads to apoptosis in the affected cancer cells, i.e. self-destruction.
Researchers hope that the use of NF-kB inhibitors such as resveratrol can significantly increase the effectiveness of already established therapeutic approaches to cancer. However, the water insolubility of resveratrol could still pose a problem: it may not be absorbed by the body in sufficient quantity and thus not sufficiently develop its effect against cancer and cardiovascular diseases.
Activation of NF-kB also plays a role in the disease progression of multiple sclerosis - therefore, NF-kB inhibitors may also be a therapeutic option in the future.
4 FOODS WHICH ARE HIGH IN RESVERATROL
Red Grapes: Grapes don't have to be fermented to contain this antioxidant. It's actually found in the skin of red grapes along with other nutrients, such as minerals manganese and potassium and vitamins K, C and B1.
Peanut Butter: Peanut butter is great for dressing up apples and celery, but it also contains some resveratrol (up to .13 mg per cup).
Dark Chocolate: In dark chocolate, resveratrol blends nicely with other antioxidants and also minerals, such as iron, copper and manganese.
Blueberries: Besides containing resveratrol as grapes, blueberries are also a great source of other antioxidants, dietary fiber, vitamins C and K and manganese.